CareShield · Janus NW Research

Genomic Nutrition Intelligence.
At the Point of Care.

Personalized dietary guidance powered by your patient's genetics, lab values, and active medications — surfaced directly in your EHR workflow.

SMART on FHIR Cerner Integrated IHS & ANTHC Focus NIH STTR R41 Pending

Standard nutrition advice ignores what makes each patient different.

1 in 3 Alaska Native adults has Type 2 diabetes. Nutrition is the primary intervention — but no provider has time to cross-reference a patient's genomic variants, lab values, and active medications to give individualized food guidance. Until now.

3.7M American Indian and Alaska Native adults with disproportionate T2DM and NAFLD burden
higher T2DM rate in Alaska Native populations compared to the U.S. national average
0 existing clinical tools cross-reference genetics, labs, and medications at the point of care

Three inputs. One coherent picture.

CareShield reads what the EHR already knows, adds what genetics reveal, and delivers a ranked, actionable nutrition plan — without disrupting the clinical workflow.

01

Patient connects their EHR

One-tap OAuth via SMART on FHIR. CareShield reads conditions, active medications, and lab values directly from Cerner, Epic, or any IHS-connected system. No manual data entry.

02

Genomic panel is uploaded

Raw 23andMe file or clinical whole-genome data. CareShield extracts 11+ metabolic SNPs — MTHFR, APOE, FADS1, TCF7L2, PNPLA3 (NAFLD risk), HFE, FUT2, and more.

03

Provider sees actionable guidance

A nutrition intelligence panel surfaces inside the EHR workflow. Drug–nutrient–gene crossovers are flagged. Foods ranked by clinical priority. One screen. Built for a 15-minute visit.

Live proof-of-concept on the Cerner SMART sandbox.

CareShield is not a whitepaper. The core infrastructure is deployed, tested, and loading real patient data from the Cerner R4 FHIR API.

SMART on FHIR Integration

Full OAuth 2.0 PKCE launch from Cerner EHR. Reads conditions, medications, labs, and patient demographics.

Live
🧬

11 Genomic Markers

MTHFR C677T/A1298C, APOE ε4, FADS1, TCF7L2, PNPLA3 (NAFLD), HFE, FUT2, CYP1A2, FTO, ALDH2.

Live
💊

Drug–Nutrient–Gene Crossover

Automatically flags when a medication depletes a nutrient that a genomic variant also impairs. Surfaced as a single actionable insight.

Live
🏥

EHR-Embedded Provider View

CareShield MPage launches inside the Cerner workflow. No new login, no context switching. The nutrition panel is part of the chart.

Live
🫀

T2DM & NAFLD Metabolic Focus

PNPLA3 rs738409, TCF7L2 rs7903146, and HFE C282Y directly target the T2DM-to-NAFLD disease spectrum prevalent in Native populations.

Proof of Concept
🔒

Privacy-First Infrastructure

Cloudflare Workers + D1 — zero patient data at rest in cloud AI systems. HIPAA-ready architecture. Data sovereignty by design.

Live

Built for populations where precision matters most.

IHS and tribal health systems carry the highest burden of metabolic disease and have the fewest tools for individualized nutrition intervention. CareShield is designed for this gap.

Alaska · Primary Site

ANMC & ANTHC

Alaska Native Medical Center (Anchorage) and the Alaska Native Tribal Health Consortium serve as our primary clinical research site. Liver Disease & Hepatitis program partnership in discussion.

Kansas · Secondary Site

Haskell Indian Nations University

100% Native American student body, Lawrence KS. IHS clinic on campus. KU Medical Center CTSA partnership nearby. Expands study from Alaska Native to pan-tribal urban Native American population.

National

IHS Network

600+ IHS-operated and tribally operated facilities nationwide. CareShield's Cerner SMART integration targets the Cerner EHR deployments that serve the majority of IHS facilities.

Disease Focus

T2DM → NAFLD Spectrum

Insulin resistance, metabolic syndrome, non-alcoholic fatty liver disease, and liver fibrosis share the same upstream nutrition drivers. CareShield targets the continuum, not just the diagnosis.

Founded in Alaska. Built on ownership.

Janus NW Research LLC is a majority Native-founded company registered in Alaska.

CEO & Co-Founder · 51%

Isabella January

Biology senior, University of Missouri–Kansas City. Majority owner and company PI for the NIH STTR R41 application. Brings academic biology foundation and patient-centered perspective to CareShield's clinical research design.

UMKC Biology · Janus NW Research LLC · Alaska
CTO & Co-Founder · 49%

Gerald January

Software engineer with 15+ years of systems and infrastructure experience. Designed and built the CareShield FHIR stack, self-hosted AI infrastructure, and the genomic nutrition intelligence engine on Cloudflare Workers + D1.

Bethel, AK · Full-stack · SMART on FHIR · Homelab AI
Advisor

Dr. Jason Burkhead, Ph.D. — Professor, Institute of Arctic Biology, University of Alaska Fairbanks. Alaska INBRE Principal Investigator and Director. Advising on bioinformatics, precision medicine, and Alaska research partnerships.

Early-stage. Traction-backed. Grant-pending.

NIH STTR R41 submission in progress. Pre-seed conversations welcome from investors who understand healthcare infrastructure and health equity.

NIH STTR R41 Grant
$400K
Phase 1 direct costs · NHGRI · Deadline Sept 8, 2026
Pre-Seed Target
$300–500K
18–24 months runway · infrastructure + research costs
Annual Infrastructure
~$55K/yr
Cloudflare · FHIR licensing · data partnerships · CommonWell
Platform Status
Live POC
Cerner SMART on FHIR · D1 · Cloudflare Workers · deployed

We are not seeking a valuation conversation yet. We want the right partners — people who understand health disparities, FHIR infrastructure, or tribal health systems.